Response to Immunotherapy

This assay enhances the prediction of a patient's response to immunotherapy in many types of cancer and helps the doctor to choose the most appropriate individualized treatment.
TMB, or tumor mutation burden, is an FDA-approved, independent predictive biomarker that has been associated with patient response to immunotherapy.
The tumor mutational burden (TMB) refers to the total number of somatic mutations present in a tumor’s genome. Tumors with a high mutation burden may have a higher rate of neo-antigens which, in principle, would be expected to be more immunogenic than tumors with comparatively low mutation burden.

Technical Characteristics of TMB Assay

The test is performed using the Oncomine™ Tumor Mutation Load Assay (409 genes). It is a robust targeted Next Generation Sequencing (NGS) assay, that provides accurate quantitation of somatic mutations to assess tumor mutation burden, in formalin-fixed, paraffin-embedded (FFPE) tissues.

For patients where their response to immunotherapy must be investigated exclusively, the Immune Response test is recommended, which includes the three biomarkers for predicting response to immunotherapy TMB, MSI & PD L1


Frequently Asked Questions

What types of cancer does it cover?

The test covers all types of cancer and helps to better predict patients’ response to immunotherapy.

In how many days will the results be available?

Results will be available within 10 working days.

What type of sample is required for the test?

A paraffin block containing the tumor tissue or unstained paraffin slides.

Is the test covered by any public/private insurance?

Fore cost coverage and related information, please contact the secretariat here.

How do I make the payment for the test?

Payment can be made by bank transfer or debit/credit card

How I send the sample and receive the results?

Regarding the receipt of the sample, please contact the secretariat. The results are shared with your doctor and with you via email.

How to order the test?

Our Customer Service Team is committed to answer your questions with regards to the services offered by Genekor. If you would like to order any of the tests that Genekor performs please contact us directly.


*To complete the test, you are required to complete and send the Consent form that you will find on the link below.

If you want to send us your sample, please contact us in order to arrange all procedures.

*For more information on scientific content please contact: